Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592910 | 0.87 | CHRM1 (0.45) | RENCHRM1BRD4CHRM5CHRM3 | |
| SCHEMBL8602365 | 0.86 | CHRM1 (0.47) | RENTSHRCHRM1CHRM5CHRM3 | |
| SCHEMBL8600207 | 0.85 | RORC (0.43) | TSHRCHRM1CHRM5CHRM3 | |
| SCHEMBL29901589 | 0.84 | CHRM1 (0.43) | TSHRCHRM1CHRM5CHRM3KMO | |
| SCHEMBL8599840 | 0.84 | CHRM1 (0.51) | RENCHRM1CHRM5CHRM3DRD2 | |
| SCHEMBL8598261 | 0.82 | CHRM1 (0.50) | RENCHRM1CHRM5CHRM3 | |
| SCHEMBL29901598 | 0.82 | CHRM1 (0.46) | RENCHRM1CHRM5CHRM3KMO | |
| SCHEMBL16526456 | 0.80 | REN (0.45) | RENTSHRCHRM1BRD4KDM4E | |
| SCHEMBL8878855 | 0.80 | CHRM1 (0.41) | TSHRCHRM1CHRM5CHRM3 | |
| SCHEMBL23577961 | 0.79 | KDM4E (0.49) | RENTSHRCHRM1KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200985-B | Pteridinone compound and preparation method and application thereof | 南开大学 | 2022-09-09 | — | — | CN | disclosed |