Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834807 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL25387147 | 0.83 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL30514054 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL666308 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL34474868 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL28831801 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL30278518 | 0.79 | PKM (0.45) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL22222078 | 0.79 | PKM (0.45) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL17934322 | 0.79 | RAB9A (0.50) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL23578587 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |