Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.56 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.56 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901773 | 0.84 | TXNRD1 (0.64) | TXNRD1TXNRD3TXNRD2RAB9AALDH1A1 | |
| SCHEMBL3798798 | 0.78 | ALDH1A1 (0.45) | RAB9AALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL31417598 | 0.78 | PARP1 (0.40) | ALDH1A1SMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL17714991 | 0.77 | TARBP2 (0.55) | TXNRD1TXNRD3TXNRD2RAB9AALDH1A1 | |
| SCHEMBL3542790 | 0.77 | MAPT (0.44) | RAB9AALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL2062068 | 0.77 | ALDH1A1 (0.49) | RAB9AALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL27797779 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KDM4EMAPTTDP1 | |
| SCHEMBL23561475 | 0.75 | KDM4E (0.43) | RAB9AALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL5666638 | 0.75 | MAPT (0.53) | RAB9AALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL6852355 | 0.75 | TARBP2 (0.46) | RAB9AALDH1A1SMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |