Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.64 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.64 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277715 | 0.87 | TXNRD1 (0.47) | TXNRD1TXNRD3TXNRD2ALDH1A1KMT2A | |
| SCHEMBL29901717 | 0.84 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2CDK2ALDH1A1 | |
| SCHEMBL9349416 | 0.78 | ALDH1A1 (0.47) | TXNRD1TXNRD3TXNRD2ALDH1A1KMT2A | |
| SCHEMBL5234315 | 0.77 | TXNRD1 (0.64) | TXNRD1TXNRD3TXNRD2CDK2ALDH1A1 | |
| SCHEMBL1613615 | 0.77 | TXNRD1 (0.55) | TXNRD1TXNRD3TXNRD2ALDH1A1KMT2A | |
| SCHEMBL773992 | 0.77 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2ALDH1A1KMT2A | |
| SCHEMBL5239589 | 0.77 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2ALDH1A1KMT2A | |
| SCHEMBL8697707 | 0.77 | TXNRD1 (0.48) | TXNRD1TXNRD3TXNRD2CDK2KMT2A | |
| SCHEMBL10749290 | 0.76 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2CDK2ALDH1A1 | |
| SCHEMBL9489186 | 0.76 | ALDH1A1 (0.46) | TXNRD1TXNRD3TXNRD2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |