Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL29978611 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL303909 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL15964647 | 0.86 | ALOX5 (0.54) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL4265304 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL13932092 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL19691246 | 0.85 | GAA (0.65) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL2954111 | 0.85 | MAPT (0.62) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL352186 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPTGAAPOLBPKM | |
| SCHEMBL9369062 | 0.83 | MAPT (0.46) | ALDH1A1MAPTGAAPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |
| WO-2023165438-A1 | TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-09-07 | — | — | WO | disclosed |
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |