Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 13/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655654 | 1.00 | MPO (0.76) | MPOTSHRSLC6A4HPGDCYP2C19 | |
| SCHEMBL4463073 | 0.92 | MPO (0.68) | MPOTSHRSLC6A4HPGDCYP2C19 | |
| SCHEMBL5203631 | 0.91 | MPO (0.80) | MPOTSHRSLC6A4HTR2ATRPM8 | |
| SCHEMBL5344966 | 0.90 | MPO (0.80) | MPOTSHRSLC6A4HTR2ATRPM8 | |
| SCHEMBL5338627 | 0.89 | MPO (0.78) | MPOTSHRSLC6A4HTR2ATRPM8 | |
| SCHEMBL5637957 | 0.88 | HTR2A (0.63) | MPOTSHRSLC6A4HPGDCYP2C19 | |
| SCHEMBL3220638 | 0.87 | MPO (0.74) | MPOTSHRSLC6A4HTR2ATRPM8 | |
| SCHEMBL2260803 | 0.84 | TSHR (1.00) | MPOTSHRSLC6A4HPGDHTR2A | |
| Hydrochloric Acid SCHEMBL1372337 | 0.83 | TSHR (0.97) | MPOTSHRSLC6A4HPGDHTR2A | |
| SCHEMBL1723364 | 0.83 | NPSR1 (0.72) | TSHRSLC6A4HPGDCYP2C19HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255830-A | S1PR2 modulators and uses thereof | 北京昌平实验室 | 2024-06-28 | — | — | CN | disclosed |
| EP-4076492-A1 | PCSK9 ANTAGONIST COMPOUNDS | Merck Sharp & Dohme LLC (US) | 2022-10-26 | — | — | EP | disclosed |