SCHEMBL29903403

SCHEMBL29903403

Fc1cnc(-n2cccn2)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
MAPK1 P28482 2/20 0.42
HTT P42858 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GRM5 P41594 3/20 0.39
KDM4E B2RXH2 3/20 0.39
LMNA P02545 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
G6PD P11413 1/20 0.39
GRM4 Q14833 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
MAPK10 P53779 1/20 0.37
KCNN4 O15554 1/20 0.36
KCNA5 P22460 1/20 0.36
CYP17A1 P05093 1/20 0.36
ADORA2A P29274 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13822152 0.83 MAPT (0.37) MAPTMAPK1HTTNPSR1L3MBTL1
SCHEMBL3377817 0.83 ADORA2A (0.41) MAPTMAPK1HTTNPSR1L3MBTL1
SCHEMBL12680215 0.79 MET (0.35) MAPTMAPK1HTTNPSR1L3MBTL1
SCHEMBL3380687 0.79 LMNA (0.56) MAPTHTTKDM4ELMNAALDH1A1
SCHEMBL15072062 0.79 GRM4 (0.35) MAPTMAPK1HTTNPSR1L3MBTL1
SCHEMBL24921598 0.79 KDM4E (0.38) MAPTMAPK1HTTNPSR1L3MBTL1
SCHEMBL10161002 0.79 MAPT (0.36) MAPTMAPK1HTTNPSR1L3MBTL1
SCHEMBL21744581 0.77 MET (0.36) MAPTMAPK1HTTNPSR1L3MBTL1
SCHEMBL21744578 0.77 MET (0.36) MAPTMAPK1HTTNPSR1L3MBTL1
SCHEMBL21744582 0.77 LMNA (0.47) MAPTNPSR1KDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618745-A1 USE OF ISOTIANIL FOR CONTROLLING PLASMODIOPHORA BRASSICA Bayer Aktiengesellschaft (DE) 2025-09-24 EP disclosed
WO-2025098875-A1 ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL/ACARICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 WO disclosed
WO-2025098876-A1 ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL/ACARICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 WO disclosed
WO-2024104643-A1 USE OF ISOTIANIL FOR CONTROLLING PLASMODIOPHORA BRASSICA BAYER AKTIENGESELLSCHAFT (DE) 2024-05-23 WO disclosed
EP-4146643-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2023-03-15 EP disclosed
EP-4065577-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-10-05 EP disclosed