Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | NPC1 | O15118 | 4/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NOS3 | P29474 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992736 | 0.91 | RAB9A (0.74) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9025242 | 0.90 | CYP2C9 (0.70) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2986625 | 0.90 | RAB9A (0.72) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2985096 | 0.89 | RAB9A (0.74) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29706525 | 0.89 | RAB9A (0.74) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8502781 | 0.89 | CYP2C9 (0.68) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2983653 | 0.89 | RAB9A (0.71) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31515434 | 0.89 | CYP2C9 (0.74) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8501307 | 0.89 | CYP2C9 (0.74) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2992805 | 0.88 | RAB9A (0.70) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778975-B2 | Helicobacter pylori eradicating agent having inhibitory activity on gastric acid secretion | Link Geonomics, Inc. (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20130012714-A1 | NOVEL SOLVATE OF DEXLANSOPRAZOLE | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2013-01-10 | — | — | US | disclosed |
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS, INC. (JP) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | GIPR, PGC, SLC10A2 | RAB9A 198/4885NPC1 1869/4885CYP1A2 2314/4885 |
| US-20130012714-A1 | NOVEL SOLVATE OF DEXLANSOPRAZOLE | CYP2D6, CYP2S1, CYP2F1 | RAB9A 1039/4885NPC1 4592/4885CYP1A2 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.