Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990364 | 0.88 | FAP (0.35) | FAPCCNE1CDK2HSP90AA1HSP90AB1 | |
| SCHEMBL2943206 | 0.87 | KDM4E (0.43) | FAPHSP90AA1HSP90AB1 | |
| SCHEMBL2942826 | 0.86 | FAP (0.35) | FAPCCNE1CDK2HSP90AA1HSP90AB1 | |
| SCHEMBL2940661 | 0.85 | FAP (0.34) | FAPCCNE1CDK2HSP90AA1HSP90AB1 | |
| SCHEMBL4274826 | 0.84 | FAP (0.36) | FAPCCNE1CDK2HSP90AA1HSP90AB1 | |
| SCHEMBL2936424 | 0.83 | HK1 (0.34) | HSP90AA1HSP90AB1CYP2C19 | |
| SCHEMBL2905785 | 0.82 | FAP (0.35) | FAP | |
| SCHEMBL2943375 | 0.78 | CCNE1 (0.40) | CCNE1CDK2HSP90AA1HSP90AB1CDK1 | |
| SCHEMBL2943371 | 0.77 | CCNE1 (0.39) | CCNE1CDK2HSP90AA1HSP90AB1CDK1 | |
| SCHEMBL2942828 | 0.76 | FAP (0.35) | FAPCCNE1CDK2HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |