SCHEMBL29904036

SCHEMBL29904036

CC(C)[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.51
▸ CTSB P07858 1/20 0.49
▸ APC P25054 1/20 0.49
▸ QRFPR Q96P65 1/20 0.49
▸ BACE1 P56817 5/20 0.48
▸ CTSD P07339 1/20 0.48
▸ OPRM1 P35372 1/20 0.48
▸ OPRD1 P41143 1/20 0.48
▸ OPRK1 P41145 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29914576 0.99 TFPI (0.50) TFPICTSBAPCQRFPRBACE1
SCHEMBL29904058 0.95 OPRD1 (0.51) CTSBBACE1CTSDOPRM1OPRD1
SCHEMBL29904037 0.88 OPRD1 (0.56) CTSBQRFPROPRM1OPRD1OPRK1
SCHEMBL29939679 0.88 APC (0.55) APCQRFPRBACE1OPRM1OPRD1
SCHEMBL29512270 0.88 APC (0.55) APCQRFPRBACE1OPRM1OPRD1
SCHEMBL31243864 0.85 BACE1 (0.52) CTSBBACE1CTSD
SCHEMBL29904057 0.84 OPRD1 (0.66) APCOPRM1OPRD1OPRK1
SCHEMBL30193614 0.84 OPRD1 (0.56) CTSBQRFPRCTSDOPRM1OPRD1
SCHEMBL29664477 0.83 NAALAD2 (0.53) APCQRFPROPRM1OPRD1
SCHEMBL31182448 0.83 TFPI (0.60) TFPIBACE1OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111200976-B Radioactive liquid embolism 微仙美国有限公司 2023-07-07 — — CN claimed
US-12569575-B2 Radiopaque particle compositions and uses thereof GUSTAVE ROUSSY TRANSFERT (FR) 2026-03-10 — — US disclosed
US-20250332261-A1 Payload-Polymer-Protein Conjugates GLYKOS FINLAND OY (FI) 2025-10-30 — — US disclosed
EP-3166638-B1 PAYLOAD-POLYMER-PROTEIN CONJUGATES GLYKOS FINLAND OY (FI) 2025-08-06 — — EP disclosed
US-11992575-B2 Radioactive liquid embolic MICROVENTION, INC. (US) 2024-05-28 — — US disclosed
US-20240108781-A1 POLYMERIC TREATMENT COMPOSITIONS MICROVENTION, INC. 2024-04-04 — — US disclosed
US-11801326-B2 Polymeric treatment compositions MICROVENTION, INC. (US) 2023-10-31 — — US disclosed
US-20220273825-A1 RADIOPAQUE PARTICLE COMPOSITIONS AND USES THEREOF GUSTAVE ROUSSY TRANSFERT (FR) 2022-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332261-A1 Payload-Polymer-Protein Conjugates TXLNA, DDOST, CD44 TFPI 1168/4885CTSB 4651/4885APC 1299/4885
US-12569575-B2 Radiopaque particle compositions and uses thereof PDGFRB, ERBB2, AKT1 TFPI 1946/4885CTSB 1284/4885APC 921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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