SCHEMBL29904058

SCHEMBL29904058

CC(C)[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 6/20 0.51
▸ OPRM1 P35372 5/20 0.51
▸ OPRK1 P41145 2/20 0.51
▸ CTSB P07858 1/20 0.50
▸ BACE1 P56817 7/20 0.49
▸ CTSD P07339 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29904036 0.95 TFPI (0.51) OPRD1OPRM1OPRK1CTSBBACE1
SCHEMBL29914576 0.94 TFPI (0.50) OPRD1OPRM1OPRK1CTSBBACE1
SCHEMBL31243864 0.90 BACE1 (0.52) CTSBBACE1CTSD
SCHEMBL31670644 0.86 TFPI (0.54) BACE1
SCHEMBL29939679 0.83 APC (0.55) OPRD1OPRM1OPRK1BACE1
SCHEMBL29512270 0.83 APC (0.55) OPRD1OPRM1OPRK1BACE1
SCHEMBL31243861 0.83 OPRD1 (0.62) OPRD1OPRM1OPRK1
SCHEMBL30686822 0.83 BACE1 (0.55) BACE1CTSD
SCHEMBL29466039 0.82 NAALAD2 (0.53) —
SCHEMBL29789582 0.82 OPRD1 (0.65) OPRD1OPRM1OPRK1CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111200976-B Radioactive liquid embolism 微仙美国有限公司 2023-07-07 — — CN claimed
US-12569575-B2 Radiopaque particle compositions and uses thereof GUSTAVE ROUSSY TRANSFERT (FR) 2026-03-10 — — US disclosed
US-11992575-B2 Radioactive liquid embolic MICROVENTION, INC. (US) 2024-05-28 — — US disclosed
US-20240108781-A1 POLYMERIC TREATMENT COMPOSITIONS MICROVENTION, INC. 2024-04-04 — — US disclosed
US-11801326-B2 Polymeric treatment compositions MICROVENTION, INC. (US) 2023-10-31 — — US disclosed
CN-111200976-B Radioactive liquid embolism 微仙美国有限公司 2023-07-07 — — CN disclosed
EP-4121130-A1 LIQUID EMBOLICS MicroVention, Inc. (US) 2023-01-25 — — EP disclosed
CN-115279427-A Liquid embolus 微仙美国有限公司 2022-11-01 — — CN disclosed
US-20220273825-A1 RADIOPAQUE PARTICLE COMPOSITIONS AND USES THEREOF GUSTAVE ROUSSY TRANSFERT (FR) 2022-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569575-B2 Radiopaque particle compositions and uses thereof PDGFRB, ERBB2, AKT1 OPRD1 2334/4885OPRM1 1480/4885OPRK1 868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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