SCHEMBL29904327

SCHEMBL29904327

CCN(C(=O)O)c1nnc(C(C)C)n1C1CC2CCC(C1)N2Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 19/20 0.49
USP2 O75604 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13915685 0.78 CCR5 (0.56) CCR5
SCHEMBL175093 0.78 CCR5 (0.56) CCR5
SCHEMBL14168719 0.76 CCR5 (0.49) CCR5
SCHEMBL12530439 0.76 ALDH1A1 (0.44) CCR5
SCHEMBL3873171 0.68 CCR5 (0.59) CCR5
SCHEMBL5354513 0.67 USP2 (0.51) USP2
SCHEMBL14155704 0.66 CCR5 (0.62) CCR5
SCHEMBL6536171 0.66 ACHE (0.50) USP2
SCHEMBL6536169 0.66 ACHE (0.50) USP2
SCHEMBL15169901 0.65 CCR5 (0.78) CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313051-A1 BIVALENT LIGANDS TO UNDERSTAND DIMERIZATION OF THE MU OPIOID RECEPTOR AND THE CHEMOKINE RECEPTOR CCR5 IN NEUROLOGICAL DISORDERS Virginia Commonwealth University (US) 2024-02-07 EP disclosed
WO-2022212471-A1 BIVALENT LIGANDS TO UNDERSTAND DIMERIZATION OF THE MU OPIOID RECEPTOR AND THE CHEMOKINE RECEPTOR CCR5 IN NEUROLOGICAL DISORDERS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2022-10-06 WO disclosed