SCHEMBL29906286

SCHEMBL29906286

COc1c(C(C)(C)C)cc2c(c1-c1ccc(C(C)(C)C)cc1)C=C(C)C2[Si](C)(C)C1C(C)=Cc2c1cc(C(C)(C)C)c(OC)c2-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 1/20 0.33
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20609994 1.00 TDO2 (0.33) TDO2KDM4EMEN1KMT2A
SCHEMBL25865218 0.96 TDO2 (0.33) TDO2
SCHEMBL25430450 0.95 TDO2 (0.30) TDO2KDM4EMEN1KMT2A
SCHEMBL31179854 0.95 TDO2 (0.30) TDO2KDM4EMEN1KMT2A
SCHEMBL15917838 0.91
SCHEMBL14645946 0.91 TDO2 (0.32) TDO2
SCHEMBL3736095 0.89 PDE4B (0.35) KDM4EMEN1KMT2A
SCHEMBL20165789 0.89 PTGS2 (0.31)
SCHEMBL29873709 0.89 PTGS2 (0.31)
SCHEMBL15808892 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111902436-B Process for preparing propylene polymers 博里利斯股份公司 2023-06-30 CN disclosed
CN-110770264-B Process for preparing heterophasic propylene copolymers 博里利斯股份公司 2022-10-14 CN disclosed