Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189773 | 0.94 | PDE4A (0.32) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15700813 | 0.93 | PDE4B (0.35) | PDE4BPDE4APDE4CPDE4DTNFRSF1A | |
| SCHEMBL14645915 | 0.91 | PDE4B (0.31) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL14645960 | 0.91 | PDE4B (0.34) | PDE4BPDE4APDE4CPDE4DTNFRSF1A | |
| SCHEMBL20609994 | 0.89 | TDO2 (0.33) | KDM4EMEN1KMT2A | |
| SCHEMBL29906286 | 0.89 | TDO2 (0.33) | KDM4EMEN1KMT2A | |
| SCHEMBL14645994 | 0.89 | — | — | |
| SCHEMBL15808892 | 0.88 | — | — | |
| SCHEMBL14645934 | 0.87 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL15808847 | 0.87 | PDE4A (0.31) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004664-B1 | METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-7834205-B2 | Metallocene compounds | Basell Polyolifine GmbH (DE) | 2010-11-16 | — | — | US | disclosed |
| US-20090275712-A1 | Metallocene Compounds | BASELL POLYOLEFINE GMBH (DE) | 2009-11-05 | — | — | US | disclosed |
| EP-2004664-A1 | METALLOCENE COMPOUNDS | Basell Polyolefine GmbH (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007116034-A1 | METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275712-A1 | Metallocene Compounds | MT-CO3, SOD1, MT-CO1 | PDE4B 4877/4885PDE4A 4835/4885PDE4C 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.