Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2993671 | 0.91 | EGFR (0.42) | MAPTMAPK1HTTALDH1A1GAA | |
| SCHEMBL14923429 | 0.80 | HTT (0.57) | MAPTMAPK1HTTALDH1A1GAA | |
| SCHEMBL2990471 | 0.79 | FERMT2 (0.65) | HTTSMN1; SMN2LMNA | |
| SCHEMBL15649292 | 0.78 | CHRNB2 (0.50) | MAPTALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL11765505 | 0.77 | KDM4E (0.57) | MAPTALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL4903360 | 0.76 | FERMT2 (0.55) | HTTALDH1A1EGFRLMNA | |
| SCHEMBL2682387 | 0.76 | MAPT (0.57) | MAPTMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3442297 | 0.76 | S1PR4 (0.58) | MAPTALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL7074338 | 0.76 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL2993675 | 0.74 | MAPT (0.41) | MAPTMAPK1HTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | AUCKLAND UNISERVICES LIMITED | 2010-07-08 | — | — | US | claimed |
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | AUCKLAND UNISERVICES LIMITED | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | BLVRB, POR, CBR3 | MAPT 3792/4885MAPK1 4517/4885HTT 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.