Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2993671 | 0.79 | EGFR (0.42) | MAPTMAPK1HTTALDH1A1GAA | |
| SCHEMBL2990677 | 0.74 | MAPT (0.46) | MAPTMAPK1HTTALDH1A1GAA | |
| SCHEMBL14923429 | 0.70 | HTT (0.57) | MAPTMAPK1HTTALDH1A1GAA | |
| SCHEMBL30122640 | 0.68 | EGFR (0.40) | MAPTMAPK1HTTALDH1A1GAA | |
| SCHEMBL4910411 | 0.63 | GPR35 (0.49) | MAPTMAPK1HTTALDH1A1GAA | |
| SCHEMBL20595200 | 0.63 | GAK (0.40) | KDR | |
| SCHEMBL12004095 | 0.62 | HSPB1 (0.46) | MAPTMAPK1HTTALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL29197536 | 0.62 | ALDH1A1 (0.37) | MAPTHTTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL30918557 | 0.62 | ALDH1A1 (0.47) | MAPTMAPK1ALDH1A1POLBMEN1 | |
| SCHEMBL12004509 | 0.61 | PDGFRA (0.57) | MAPTHTTMEN1KMT2APDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | AUCKLAND UNISERVICES LIMITED | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | BLVRB, POR, CBR3 | MAPT 3792/4885MAPK1 4517/4885HTT 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.