⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210784 | 1.00 | — | — | |
| SCHEMBL23211053 | 0.93 | — | — | |
| SCHEMBL29907065 | 0.93 | — | — | |
| SCHEMBL29907197 | 0.89 | CNR1 (0.34) | — | |
| SCHEMBL23211133 | 0.89 | CNR1 (0.34) | — | |
| SCHEMBL29008870 | 0.76 | GPR84 (0.33) | — | |
| SCHEMBL23264127 | 0.74 | MAP4K1 (0.46) | — | |
| SCHEMBL23211081 | 0.72 | DGAT1 (0.31) | — | |
| SCHEMBL29907092 | 0.72 | DGAT1 (0.31) | — | |
| SCHEMBL23210897 | 0.70 | AXL (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |