Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23211133 | 1.00 | CNR1 (0.34) | CNR1CNR2TTKDRD4IRAK1 | |
| SCHEMBL23211053 | 0.90 | — | — | |
| SCHEMBL29907065 | 0.90 | — | — | |
| SCHEMBL29907100 | 0.89 | — | — | |
| SCHEMBL23210784 | 0.89 | — | — | |
| SCHEMBL23210897 | 0.79 | AXL (0.35) | CNR1CNR2 | |
| SCHEMBL29907138 | 0.79 | AXL (0.35) | CNR1CNR2 | |
| SCHEMBL29008870 | 0.78 | GPR84 (0.33) | DRD4IRAK1 | |
| SCHEMBL19948747 | 0.74 | DGAT1 (0.33) | CNR2TTK | |
| SCHEMBL23211081 | 0.74 | DGAT1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |