Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 3/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210897 | 1.00 | AXL (0.35) | AXLDGAT1PGK1CNR2CNR1 | |
| SCHEMBL19948747 | 0.83 | DGAT1 (0.33) | AXLDGAT1PGK1CNR2FGFR3 | |
| SCHEMBL1330040 | 0.79 | AXL (0.46) | AXLDGAT1 | |
| SCHEMBL23211133 | 0.79 | CNR1 (0.34) | CNR2CNR1 | |
| SCHEMBL29907197 | 0.79 | CNR1 (0.34) | CNR2CNR1 | |
| SCHEMBL29907034 | 0.78 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL23211119 | 0.78 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL19950254 | 0.77 | CREBBP (0.33) | AXLDGAT1PGK1 | |
| SCHEMBL30070423 | 0.77 | CREBBP (0.33) | AXLDGAT1PGK1 | |
| SCHEMBL22892770 | 0.77 | MET (0.46) | AXLPGK1FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |