Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210858 | 1.00 | S1PR1 (0.32) | S1PR1DGAT1CD274CHEK1 | |
| SCHEMBL23211014 | 0.87 | DGAT1 (0.30) | S1PR1DGAT1 | |
| SCHEMBL29907130 | 0.87 | DGAT1 (0.30) | S1PR1DGAT1 | |
| SCHEMBL23210980 | 0.86 | S1PR1 (0.32) | S1PR1 | |
| SCHEMBL29907117 | 0.82 | KDM1A (0.36) | DGAT1 | |
| SCHEMBL23211098 | 0.82 | KDM1A (0.36) | DGAT1 | |
| SCHEMBL29907115 | 0.81 | DGAT1 (0.35) | S1PR1DGAT1CHEK1 | |
| SCHEMBL23210803 | 0.81 | DGAT1 (0.35) | S1PR1DGAT1CHEK1 | |
| SCHEMBL23264044 | 0.77 | CHEK1 (0.41) | S1PR1CHEK1 | |
| SCHEMBL30308806 | 0.77 | TBK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |