Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27143647 | 1.00 | NPC1 (0.34) | NPC1BRD4CREBBPDGAT1EGFR | |
| SCHEMBL27141668 | 0.84 | BRD4 (0.37) | NPC1BRD4CREBBPDGAT1KMT2A | |
| SCHEMBL30897277 | 0.84 | BRD4 (0.37) | NPC1BRD4CREBBPDGAT1KMT2A | |
| SCHEMBL27138820 | 0.81 | BRD4 (0.34) | NPC1BRD4CREBBPDGAT1EGFR | |
| SCHEMBL29907280 | 0.81 | BRD4 (0.34) | NPC1BRD4CREBBPDGAT1EGFR | |
| SCHEMBL22717628 | 0.78 | ALDH1A1 (0.38) | NPC1DGAT1KMT2AMAPT | |
| SCHEMBL27251284 | 0.78 | BRD4 (0.33) | BRD4CREBBPDGAT1EGFRIGF1R | |
| SCHEMBL29907301 | 0.77 | KMT2A (0.38) | NPC1BRD4CREBBPDGAT1EGFR | |
| SCHEMBL27139837 | 0.77 | KMT2A (0.38) | NPC1BRD4CREBBPDGAT1EGFR | |
| SCHEMBL15825447 | 0.75 | DGAT1 (0.40) | NPC1BRD4CREBBPDGAT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602047-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | The Universite de Montreal (CA) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |
| EP-4326719-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022221939-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2022-10-27 | — | — | WO | disclosed |