SCHEMBL29908289

SCHEMBL29908289

Cc1ccc(O)c(Cc2cc(C3(c4cc(Cc5cc(C)ccc5O)c(O)c(C5CCCCC5)c4)CCCCC3)cc(C3CCCCC3)c2O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.48
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
ACHE P22303 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.36
NUDT1 P36639 1/20 0.34
BACE1 P56817 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HTT P42858 2/20 0.32
NPC1 O15118 2/20 0.32
GAA P10253 2/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP2C19 P33261 2/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31
SLC2A1 P11166 1/20 0.31
GLA P06280 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30374839 1.00 AMY1A (0.48) AMY1AESR1ESR2ACHEPTGDR2
SCHEMBL3199214 1.00 AMY1A (0.48) AMY1AESR1ESR2ACHEPTGDR2
SCHEMBL29831687 0.85 ESR1 (0.37) ESR1ESR2ACHENUDT1BACE1
SCHEMBL3194500 0.85 ESR1 (0.37) ESR1ESR2ACHENUDT1BACE1
SCHEMBL30375240 0.85 ESR1 (0.37) ESR1ESR2ACHENUDT1BACE1
SCHEMBL4455212 0.84 HSP90AA1 (0.34) ESR1ESR2ACHENUDT1BACE1
SCHEMBL13708135 0.83 ESR1 (0.48) ESR1ESR2ACHENUDT1BACE1
SCHEMBL2611794 0.83 ACHE (0.56) AMY1AESR1ESR2ACHEHSP90AA1
SCHEMBL278223 0.83 ACHE (0.43) ESR1ESR2ACHENUDT1BACE1
SCHEMBL29644928 0.83 ACHE (0.43) ESR1ESR2ACHENUDT1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875110-A Polyphenylene ether, polyphenylene ether solution, resin film, prepreg, and metal-clad laminate 旭化成株式会社 2025-04-25 CN claimed
US-20240166812-A1 POLYPHENYLENE ETHER, PRODUCTION METHOD OF THE SAME, THERMOSETTING COMPOSITION, PREPREG, AND LAMINATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-05-23 US disclosed
CN-117106172-A Polyphenylene ether, resin composition, resin film, prepreg, and metal-clad laminate 旭化成株式会社 2023-11-24 CN disclosed
CN-116888186-A Polyphenylene ether, method for producing the same, heat-curable composition, prepreg, and laminate 旭化成株式会社 2023-10-13 CN disclosed
CN-112812291-B Hydrogenated polyphenylene ether and process for producing the same 旭化成株式会社 2023-07-18 CN disclosed
WO-2022239631-A1 NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2022-11-17 WO disclosed
WO-2022190497-A1 POLYPHENYLENE ETHER, METHOD FOR PRODUCING SAME, THERMALLY CURABLE COMPOSITION, PREPREG, AND MULTILAYER BODY 旭化成株式会社 2022-09-15 WO disclosed