SCHEMBL278223

SCHEMBL278223

Cc1cc(O)c(C2CCCCC2)cc1Cc1cc(C2(c3cc(Cc4cc(C5CCCCC5)c(O)cc4C)c(O)c(C4CCCCC4)c3)CCCCC2)cc(C2CCCCC2)c1O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
NUDT1 P36639 1/20 0.32
BACE1 P56817 1/20 0.32
HSP90AA1 P07900 1/20 0.32
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29644928 1.00 ACHE (0.43) ACHEESR1ESR2NUDT1BACE1
SCHEMBL3197348 0.83 ACHE (0.52) ACHEESR1ESR2NUDT1BACE1
SCHEMBL30375037 0.83 ACHE (0.52) ACHEESR1ESR2NUDT1BACE1
SCHEMBL29908289 0.83 AMY1A (0.48) ACHEESR1ESR2NUDT1BACE1
SCHEMBL30374839 0.83 AMY1A (0.48) ACHEESR1ESR2NUDT1BACE1
SCHEMBL3199214 0.83 AMY1A (0.48) ACHEESR1ESR2NUDT1BACE1
SCHEMBL278212 0.82 NUDT1 (0.43) NUDT1BACE1HSP90AA1
SCHEMBL30677888 0.82 NUDT1 (0.43) NUDT1BACE1HSP90AA1
SCHEMBL13708135 0.82 ESR1 (0.48) ACHEESR1ESR2NUDT1BACE1
SCHEMBL3173227 0.81 ACHE (0.42) ACHEESR1ESR2NUDT1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
EP-4306571-B1 POLYPHENYLENE ETHER, METHOD FOR PRODUCING SAME, THERMALLY CURABLE COMPOSITION, PREPREG, AND MULTILAYER BODY ASAHI CHEMICAL IND (JP) 2024-12-25 EP disclosed
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
EP-4306571-A1 POLYPHENYLENE ETHER, METHOD FOR PRODUCING SAME, THERMALLY CURABLE COMPOSITION, PREPREG, AND MULTILAYER BODY Asahi Kasei Kabushiki Kaisha (JP) 2024-01-17 EP disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed
US-20220356302-A1 POLYPHENYLENE ETHER COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-11-10 US disclosed
EP-4039728-A1 POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2022-08-10 EP disclosed
WO-2020209118-A1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME 株式会社パイロットコーポレーション 2020-10-15 WO disclosed
WO-2020203603-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME パイロットインキ株式会社 2020-10-08 WO disclosed
EP-2628760-A1 POLYPHENYLENE ETHER POWDER AND POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-08-21 EP disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed
US-8133550-B2 Good breaking elongation characteristics, achievable high sensitivity and high film remaining rate, little in pattern size fluctuation at the heating time after lithographic process, capable of stable pattern formation; manufacturing a semiconductor device FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-8133550-B2 Good breaking elongation characteristics, achievable high sensitivity and high film remaining rate, little in pattern size fluctuation at the heating time after lithographic process, capable of stable pattern formation; manufacturing a semiconductor device FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-7662906-B2 Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-16 US disclosed
US-20080076849-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080076849-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20070213499-A1 Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-13 US disclosed
EP-1832617-A2 Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof Mitsubishi Gas Chemical Company, Inc. (JP) 2007-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE CD79B, BRIX1, SMARCB1 ACHE 4165/4885ESR1 383/4885ESR2 1987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.