Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 11/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908423 | 0.82 | NR3C2 (0.39) | LTA4HNR3C2RIPK1 | |
| SCHEMBL29908458 | 0.81 | PARP1 (0.39) | NOTUMLTA4HNR3C2RIPK1 | |
| SCHEMBL29908490 | 0.79 | RIPK1 (0.38) | LTA4HNR3C2RIPK1 | |
| SCHEMBL21806848 | 0.71 | MEN1 (0.48) | LTA4H | |
| SCHEMBL21807029 | 0.71 | MEN1 (0.48) | LTA4H | |
| SCHEMBL21807075 | 0.71 | MEN1 (0.48) | LTA4H | |
| SCHEMBL25551288 | 0.70 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL25551290 | 0.70 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL31244841 | 0.70 | MEN1 (0.53) | LTA4H | |
| SCHEMBL4716719 | 0.69 | CD74 (0.40) | NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028649-A | Tricyclic compound, pharmaceutical composition containing same and use thereof | 四川科伦博泰生物医药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |