Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 18/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908470 | 0.79 | NOTUM (0.42) | RIPK1NR3C2LTA4H | |
| SCHEMBL11558878 | 0.77 | NOTUM (0.41) | RIPK1 | |
| SCHEMBL29908423 | 0.76 | NR3C2 (0.39) | RIPK1NR3C2LTA4H | |
| SCHEMBL29908458 | 0.75 | PARP1 (0.39) | RIPK1NR3C2LTA4H | |
| SCHEMBL30250644 | 0.71 | CHRNB4 (0.36) | RIPK1NR3C2LTA4H | |
| SCHEMBL31025716 | 0.71 | CHRNB4 (0.36) | RIPK1NR3C2LTA4H | |
| SCHEMBL24640361 | 0.71 | HTR2A (0.45) | RIPK1NR3C2LTA4H | |
| SCHEMBL24640162 | 0.71 | HTR2A (0.45) | RIPK1NR3C2LTA4H | |
| SCHEMBL25551288 | 0.70 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL25551290 | 0.70 | RIPK1 (0.47) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028649-A | Tricyclic compound, pharmaceutical composition containing same and use thereof | 四川科伦博泰生物医药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |