Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908470 | 0.82 | NOTUM (0.42) | NR3C2RIPK1LTA4H | |
| SCHEMBL29908458 | 0.78 | PARP1 (0.39) | NR3C2RIPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7471047 | 0.77 | NOTUM (0.43) | ALDH1A1LMNALTA4H | |
| SCHEMBL29908490 | 0.76 | RIPK1 (0.38) | NR3C2RIPK1LTA4H | |
| SCHEMBL26914996 | 0.71 | HTR2A (0.58) | — | |
| SCHEMBL31022150 | 0.71 | HTR2A (0.58) | — | |
| SCHEMBL31022237 | 0.70 | HTR2A (0.42) | NR3C2 | |
| SCHEMBL4716719 | 0.70 | CD74 (0.40) | NR3C2ALDH1A1LMNAPOLBADORA3 | |
| SCHEMBL21807029 | 0.69 | MEN1 (0.48) | LTA4H | |
| SCHEMBL21807075 | 0.69 | MEN1 (0.48) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028649-A | Tricyclic compound, pharmaceutical composition containing same and use thereof | 四川科伦博泰生物医药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |