Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757115 | 0.98 | RIPK1 (0.39) | RIPK1LTA4HGAAPDE10AHPGD | |
| SCHEMBL20798385 | 0.74 | PDE10A (0.39) | RIPK1LTA4HPDE10ANISCHMEN1 | |
| SCHEMBL21187104 | 0.74 | NISCH (0.36) | RIPK1LTA4HNISCHHTTMEN1 | |
| SCHEMBL20798386 | 0.74 | PDE10A (0.39) | RIPK1LTA4HPDE10ANISCHMEN1 | |
| SCHEMBL14421731 | 0.74 | CREBBP (0.39) | LTA4HGAA | |
| SCHEMBL19859198 | 0.73 | RIPK1 (0.41) | RIPK1LTA4HGAAHPGDTSHR | |
| SCHEMBL3587691 | 0.73 | — | — | |
| SCHEMBL5466546 | 0.72 | GAA (0.57) | GAAHPGDNISCHHTTSMN1; SMN2 | |
| SCHEMBL28857808 | 0.72 | — | — | |
| SCHEMBL26373004 | 0.71 | LTA4H (0.34) | RIPK1LTA4HTSHRNISCHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028649-A | Tricyclic compound, pharmaceutical composition containing same and use thereof | 四川科伦博泰生物医药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |