Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17383846 | 0.77 | IMPDH2 (0.73) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL16169793 | 0.74 | IMPDH2 (0.69) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL29678164 | 0.73 | IMPDH2 (0.58) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL6986423 | 0.71 | IMPDH2 (0.65) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL27701196 | 0.71 | IMPDH2 (0.65) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL8722197 | 0.71 | IMPDH2 (0.65) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL4607984 | 0.71 | ESR1 (0.69) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL31060312 | 0.71 | IMPDH2 (1.00) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL8722153 | 0.71 | IMPDH2 (0.65) | IMPDH2AHRMAPTALDH1A1LMNA | |
| SCHEMBL28643376 | 0.71 | IMPDH2 (0.59) | IMPDH2AHRMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11466252-B2 | Expansion and differentiation of inner ear supporting cells and methods of use thereof | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2022-10-11 | — | — | US | disclosed |