SCHEMBL2990890

SCHEMBL2990890

C1CCC2CC(C3CCCC4CCCCC43)CCC2C1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
HSD11B1 P28845 1/20 0.33
EPAS1 Q99814 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3765866 0.89 ALDH1A1 (0.37) ALDH1A1HSD11B1EPAS1
SCHEMBL6688863 0.88 ALDH1A1 (0.47) ALDH1A1HSD11B1EPAS1
SCHEMBL13464122 0.88 ALDH1A1 (0.47) ALDH1A1HSD11B1EPAS1
SCHEMBL2996759 0.86 MAPT (0.33) ALDH1A1
SCHEMBL2011115 0.85 ALDH1A1 (0.35) ALDH1A1HSD11B1EPAS1
SCHEMBL1154960 0.85 ALDH1A1 (0.44) ALDH1A1HSD11B1EPAS1
SCHEMBL6689602 0.85 ALDH1A1 (0.44) ALDH1A1HSD11B1EPAS1
SCHEMBL212308 0.85 ALDH1A1 (0.50) ALDH1A1HSD11B1EPAS1
SCHEMBL173214 0.85 HSD11B1 (0.34) ALDH1A1HSD11B1
SCHEMBL20511602 0.85 HSD11B1 (0.34) ALDH1A1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
EP-0224259-B1 A WORKING FLUID FOR TRACTION DRIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-02-10 EP disclosed
US-4684754-A DECAHYDRONAPHTHALENE DERIVATIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-08-04 US disclosed
EP-0224259-A2 A working fluid for traction drive IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-06-03 EP disclosed
US-4521324-A Fluid for traction drive IDEMITSU KOSAN COMPANY LIMITED (JP) 1985-06-04 US disclosed