Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | PTGES | O14684 | 4/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909172 | 0.84 | — | — | |
| SCHEMBL29909078 | 0.83 | PTGDR2 (0.37) | PTGDR2CYP1A2SCN9AALDH1A1RECQL | |
| SCHEMBL29909566 | 0.82 | KDM4C (0.30) | — | |
| SCHEMBL23601064 | 0.81 | CYP1A2 (0.34) | CYP1A2SCN9APTGESALDH1A1RECQL | |
| SCHEMBL29909640 | 0.79 | KDM1A (0.34) | — | |
| SCHEMBL29909790 | 0.74 | NR3C1 (0.37) | PTGDR2GRIN2BTDO2 | |
| SCHEMBL29909849 | 0.74 | SCN9A (0.37) | PTGDR2CYP1A2SCN9APTGESALDH1A1 | |
| SCHEMBL30979130 | 0.74 | — | — | |
| SCHEMBL29909035 | 0.72 | RPLP1 (0.31) | — | |
| SCHEMBL29909783 | 0.72 | DHODH (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |