Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.31 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909790 | 0.92 | NR3C1 (0.37) | PTGDR2ABCG2DHODHFYNTDO2 | |
| SCHEMBL29909849 | 0.92 | SCN9A (0.37) | PTGDR2ALDH1A1RECQLSCN9AABCG2 | |
| SCHEMBL29909783 | 0.89 | DHODH (0.37) | ABCG2DHODHGRM5NR3C1ATM | |
| SCHEMBL29909148 | 0.86 | DHODH (0.39) | SCN9AABCG2DHODHNR3C1 | |
| SCHEMBL29909452 | 0.85 | DHODH (0.38) | SCN9AABCG2DHODHCYP1A2 | |
| SCHEMBL29909747 | 0.84 | ABCG2 (0.36) | ABCG2DHODH | |
| SCHEMBL29909012 | 0.83 | PTGDR2 (0.39) | PTGDR2ALDH1A1RECQLSCN9ATDO2 | |
| SCHEMBL29909513 | 0.83 | ABCG2 (0.35) | PTGDR2ABCG2DHODH | |
| SCHEMBL29909517 | 0.83 | DHODH (0.36) | ABCG2DHODHNR3C1 | |
| SCHEMBL29909252 | 0.81 | ABCG2 (0.45) | ABCG2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |