Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909078 | 0.92 | PTGDR2 (0.37) | NR3C1ABCG2DHODHPTGDR2FYN | |
| SCHEMBL29909517 | 0.86 | DHODH (0.36) | NR3C1ABCG2DHODH | |
| SCHEMBL29909783 | 0.85 | DHODH (0.37) | NR3C1ABCG2DHODHNR1H4ATM | |
| SCHEMBL29909747 | 0.85 | ABCG2 (0.36) | ABCG2DHODH | |
| SCHEMBL29909513 | 0.84 | ABCG2 (0.35) | ABCG2DHODHPTGDR2 | |
| SCHEMBL29909849 | 0.83 | SCN9A (0.37) | ABCG2PTGDR2FYNGRIN2BATM | |
| SCHEMBL29909893 | 0.83 | ABCG2 (0.35) | ABCG2DHODHTDO2 | |
| SCHEMBL29909452 | 0.83 | DHODH (0.38) | ABCG2DHODHCYP2C9 | |
| SCHEMBL29909148 | 0.82 | DHODH (0.39) | NR3C1ABCG2DHODHPIK3CAGRIN2B | |
| SCHEMBL29909252 | 0.82 | ABCG2 (0.45) | ABCG2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |