Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909024 | 0.90 | ABCG2 (0.37) | DHODHABCG2SCN9ADHFRPDE2A | |
| SCHEMBL29909561 | 0.90 | ABCG2 (0.35) | DHODHABCG2NR3C1PGRTDP1 | |
| SCHEMBL29909452 | 0.89 | DHODH (0.38) | DHODHABCG2SCN9A | |
| SCHEMBL29909783 | 0.89 | DHODH (0.37) | DHODHABCG2NR3C1PGRNT5E | |
| SCHEMBL29909078 | 0.86 | PTGDR2 (0.37) | DHODHABCG2NR3C1SCN9A | |
| SCHEMBL29909909 | 0.86 | DHODH (0.41) | DHODHABCG2 | |
| SCHEMBL29909252 | 0.85 | ABCG2 (0.45) | DHODHABCG2 | |
| SCHEMBL29909517 | 0.84 | DHODH (0.36) | DHODHABCG2NR3C1PDE2A | |
| SCHEMBL29909829 | 0.83 | ABCG2 (0.36) | DHODHABCG2 | |
| SCHEMBL29909871 | 0.82 | ABCG2 (0.40) | DHODHABCG2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |