Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576965 | 1.00 | TP53 (0.37) | TP53ALDH1A1PLAUABCB1TUBB3 | |
| SCHEMBL23577063 | 0.90 | ABCG2 (0.38) | ALDH1A1PDGFRBEGFRKDR | |
| SCHEMBL29909869 | 0.90 | ABCG2 (0.38) | ALDH1A1PDGFRBEGFRKDR | |
| SCHEMBL24721227 | 0.90 | TP53 (0.41) | TP53ALDH1A1KMT2AMAPTPDGFRB | |
| SCHEMBL29909005 | 0.89 | MAPT (0.33) | TP53ALDH1A1MEN1NPC1PKM | |
| SCHEMBL23576893 | 0.89 | MAPT (0.33) | TP53ALDH1A1MEN1NPC1PKM | |
| SCHEMBL29909398 | 0.89 | TP53 (0.37) | TP53ALDH1A1MAPTPDGFRBEGFR | |
| SCHEMBL23600785 | 0.89 | TP53 (0.37) | TP53ALDH1A1MAPTPDGFRBEGFR | |
| SCHEMBL23576643 | 0.89 | NPM1 (0.39) | TP53ALDH1A1ABCB1MAPTPDGFRB | |
| SCHEMBL29909114 | 0.89 | NPM1 (0.39) | TP53ALDH1A1ABCB1MAPTPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |