Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576893 | 1.00 | MAPT (0.33) | MAPTALDH1A1TSHRMAPK1DHODH | |
| SCHEMBL23577063 | 0.93 | ABCG2 (0.38) | ALDH1A1TSHRMAPK1DHODHABCG2 | |
| SCHEMBL29909869 | 0.93 | ABCG2 (0.38) | ALDH1A1TSHRMAPK1DHODHABCG2 | |
| SCHEMBL29909160 | 0.91 | ABCG2 (0.38) | MAPTDHODHLRRK2ABCG2TP53 | |
| SCHEMBL23577162 | 0.91 | ABCG2 (0.38) | MAPTDHODHLRRK2ABCG2TP53 | |
| SCHEMBL23576965 | 0.89 | TP53 (0.37) | MAPTALDH1A1TP53NPC1HPGD | |
| SCHEMBL29909323 | 0.89 | TP53 (0.37) | MAPTALDH1A1TP53NPC1HPGD | |
| SCHEMBL23576865 | 0.88 | MAPT (0.33) | MAPTALDH1A1TSHRMAPK1DHODH | |
| SCHEMBL23577190 | 0.88 | MAT2A (0.37) | MAPTALDH1A1TP53KDM4ENPC1 | |
| SCHEMBL29909135 | 0.88 | MAT2A (0.37) | MAPTALDH1A1TP53KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |