SCHEMBL29909372

SCHEMBL29909372

C#CC(O)(Cc1cccc(N(C)c2nc3nncn3c3cc(Cl)ccc23)c1)C1(C)CC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29909515 0.88 MAPT (0.33) MAT2A
SCHEMBL29909800 0.86 MAT2A (0.32) MAT2A
SCHEMBL29909281 0.84 MAT2A (0.31) MAT2A
SCHEMBL23578135 0.79 MAT2A (0.32) MAT2A
SCHEMBL29909480 0.79 MAPT (0.34) MAT2A
SCHEMBL23601289 0.77 MAT2A (0.34) MAT2A
SCHEMBL29909842 0.77 FNTA (0.33)
SCHEMBL29909653 0.77 SMN1; SMN2 (0.31) MAT2A
SCHEMBL23601355 0.76 MAT2A (0.32) MAT2A
SCHEMBL29909947 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed