Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909515 | 0.90 | MAPT (0.33) | MAPTTP53FNTAFNTBPRMT5 | |
| SCHEMBL23577465 | 0.82 | PTGES (0.35) | MAPTTP53FNTAFNTBPRMT5 | |
| SCHEMBL29909653 | 0.80 | SMN1; SMN2 (0.31) | MAPTMAT2ASMN1; SMN2 | |
| SCHEMBL29909800 | 0.80 | MAT2A (0.32) | MAPTTP53FNTAFNTBPRMT5 | |
| SCHEMBL23577387 | 0.80 | MAT2A (0.36) | MAPTTP53FNTAFNTBPRMT5 | |
| SCHEMBL29909567 | 0.80 | MAT2A (0.36) | MAPTTP53FNTAFNTBPRMT5 | |
| SCHEMBL29909281 | 0.79 | MAT2A (0.31) | MAT2A | |
| SCHEMBL29909372 | 0.79 | MAT2A (0.31) | MAT2A | |
| SCHEMBL29909947 | 0.78 | — | — | |
| SCHEMBL29909979 | 0.77 | PAK4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |