Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672267 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL29909484 | 0.76 | PDE2A (0.30) | — | |
| SCHEMBL23577002 | 0.76 | PDE2A (0.30) | — | |
| SCHEMBL30012748 | 0.72 | PDPK1 (0.47) | HTT | |
| SCHEMBL7336294 | 0.72 | PDPK1 (0.47) | HTT | |
| SCHEMBL30679217 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL29021119 | 0.69 | HTT (0.35) | HTT | |
| SCHEMBL25235791 | 0.68 | HTT (0.31) | HTT | |
| SCHEMBL17884009 | 0.68 | AMY1A (0.33) | HTTAMY1AERN1 | |
| SCHEMBL9446919 | 0.65 | CYP3A4 (0.37) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106488910-A | Inhibitors of kras g12c | 亚瑞克西斯制药公司 | 2017-03-08 | — | — | CN | disclosed |