Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909353 | 0.90 | ABCG2 (0.37) | NPC1POLBGAARAB9ARXFP1 | |
| SCHEMBL29909708 | 0.89 | ABCG2 (0.41) | NPC1POLBGAARAB9ARXFP1 | |
| SCHEMBL29909298 | 0.88 | CFTR (0.36) | NPC1POLBGAARAB9ARXFP1 | |
| SCHEMBL29909361 | 0.88 | HSD17B1 (0.39) | ABCG2PSDPDE5A | |
| SCHEMBL29909750 | 0.87 | ABCG2 (0.36) | NPC1POLBGAARAB9ARXFP1 | |
| SCHEMBL29909687 | 0.86 | ABCG2 (0.37) | ABCG2PDE5ADHODH | |
| SCHEMBL29909758 | 0.86 | ABCG2 (0.37) | ABCG2PDE5ADHODH | |
| SCHEMBL29909705 | 0.86 | ABCG2 (0.37) | NPC1POLBGAARAB9ARXFP1 | |
| SCHEMBL29909542 | 0.85 | ABCG2 (0.34) | ABCG2PDE5A | |
| SCHEMBL30961080 | 0.85 | CNR2 (0.38) | ABCG2TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |