Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909741 | 0.88 | NPC1 (0.43) | ADKNPC1POLBGAARAB9A | |
| SCHEMBL29909361 | 0.85 | HSD17B1 (0.39) | ABCG2 | |
| SCHEMBL29909353 | 0.83 | ABCG2 (0.37) | NPC1POLBGAARAB9ARXFP1 | |
| SCHEMBL29909708 | 0.83 | ABCG2 (0.41) | NPC1POLBGAARAB9ARXFP1 | |
| SCHEMBL29909750 | 0.82 | ABCG2 (0.36) | NPC1POLBGAARAB9ARXFP1 | |
| SCHEMBL29909849 | 0.82 | SCN9A (0.37) | DGAT1ABCG2FYN | |
| SCHEMBL29909568 | 0.81 | TNKS (0.38) | — | |
| SCHEMBL23601614 | 0.81 | ADK (0.36) | CFTRDGAT1ADKMEN1KMT2A | |
| SCHEMBL29909687 | 0.80 | ABCG2 (0.37) | ABCG2PIK3CA | |
| SCHEMBL29909705 | 0.80 | ABCG2 (0.37) | NPC1POLBGAARAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | DGKG, DGKB, DGKK | CFTR 3469/4885DGAT1 17/4885ADK 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.