Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 10/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578111 | 1.00 | GRM5 (0.34) | GRM5MAT2AFNTAFNTBPRMT5 | |
| SCHEMBL23601797 | 0.88 | MAT2A (0.34) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL29909485 | 0.88 | MAT2A (0.34) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL29909770 | 0.86 | TSHR (0.39) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL23577711 | 0.86 | TSHR (0.39) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL23601269 | 0.86 | F10 (0.40) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL23600544 | 0.85 | ENPP2 (0.36) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL24721684 | 0.85 | FNTA (0.35) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL23601235 | 0.84 | FNTA (0.40) | MAT2AFNTAFNTBPRMT5CYP1A2 | |
| SCHEMBL29909768 | 0.84 | FNTA (0.40) | MAT2AFNTAFNTBPRMT5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |