Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 4/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577711 | 1.00 | TSHR (0.39) | TSHRF10PDE10AMAPTLMNA | |
| SCHEMBL23601269 | 0.98 | F10 (0.40) | TSHRF10PDE10AMAPTLMNA | |
| SCHEMBL29909485 | 0.95 | MAT2A (0.34) | TSHRF10MAPTMAT2APRMT5 | |
| SCHEMBL23601797 | 0.95 | MAT2A (0.34) | TSHRF10MAPTMAT2APRMT5 | |
| SCHEMBL23600544 | 0.87 | ENPP2 (0.36) | MAPTMAT2APRMT5FNTAFNTB | |
| SCHEMBL24721684 | 0.87 | FNTA (0.35) | MAPTMAT2APRMT5FNTAFNTB | |
| SCHEMBL29909756 | 0.86 | GRM5 (0.34) | MAT2APRMT5FNTAFNTBCYP1A2 | |
| SCHEMBL23578111 | 0.86 | GRM5 (0.34) | MAT2APRMT5FNTAFNTBCYP1A2 | |
| SCHEMBL23601235 | 0.85 | FNTA (0.40) | F10MAPTMAT2APRMT5FNTA | |
| SCHEMBL29909768 | 0.85 | FNTA (0.40) | F10MAPTMAT2APRMT5FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |