Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577285 | 1.00 | KDM4E (0.44) | KDM4EMAPTRAB9APOLBNPC1 | |
| SCHEMBL23577034 | 0.87 | MAPT (0.44) | KDM4EMAPTRAB9APOLBNPC1 | |
| SCHEMBL29909113 | 0.87 | MAPT (0.44) | KDM4EMAPTRAB9APOLBNPC1 | |
| SCHEMBL23601680 | 0.85 | NPC1 (0.43) | MAPTRAB9ANPC1CYP3A4ALDH1A1 | |
| SCHEMBL23601086 | 0.84 | KDM4E (0.61) | KDM4EMAPTRAB9APOLBNPC1 | |
| SCHEMBL29909620 | 0.74 | NPC1 (0.41) | MAPTNPC1ALDH1A1GAA | |
| SCHEMBL23576644 | 0.74 | NPC1 (0.41) | MAPTNPC1ALDH1A1GAA | |
| SCHEMBL29909270 | 0.71 | MAPT (0.43) | KDM4EMAPTPOLBNPC1ALDH1A1 | |
| SCHEMBL23577291 | 0.71 | MAPT (0.43) | KDM4EMAPTPOLBNPC1ALDH1A1 | |
| SCHEMBL23576960 | 0.71 | NPC1 (0.49) | KDM4EMAPTRAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |