Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343737 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTHDAC1HDAC8HDAC3 | |
| SCHEMBL5339617 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTHDAC1HDAC8HDAC3 | |
| SCHEMBL24904273 | 0.81 | GRM5 (0.49) | ALDH1A1MAPTHDAC1HDAC8HDAC3 | |
| SCHEMBL9127426 | 0.80 | ALDH1A1 (0.57) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL25669884 | 0.80 | SMN1; SMN2 (0.52) | ALDH1A1MAPTHDAC1HDAC8HDAC3 | |
| SCHEMBL10354572 | 0.77 | HSD17B10 (0.55) | ALDH1A1GLRA3GLRBKDM2BKMT2A | |
| SCHEMBL31647146 | 0.76 | GAA (0.48) | CA12CA9CA1CA2ALDH1A1 | |
| Pyrrole SCHEMBL10572488 | 0.76 | HDAC1 (0.47) | ALDH1A1MAPTHDAC1HDAC8HDAC3 | |
| SCHEMBL38665929 | 0.73 | CA12 (0.52) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL212673 | 0.73 | MAPT (0.61) | ALDH1A1MAPTHDAC1HDAC8GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11464784-B2 | Inhibition of aminocylase 3 (AA3) in the treatment of cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-10-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11464784-B2 | Inhibition of aminocylase 3 (AA3) in the treatment of cancer | PLAAT3, HCCS, LAP3 | CA12 991/4885CA9 766/4885CA1 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.