Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.34 |
| ▸ | MAP3K9 | P80192 | 5/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | MAP3K10 | Q02779 | 2/20 | 0.31 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063519 | 1.00 | CA1 (0.36) | CA1CA2CA4CA6BCHE | |
| SCHEMBL29809978 | 1.00 | CA1 (0.36) | CA1CA2CA4CA6BCHE | |
| SCHEMBL12952436 | 0.91 | CA1 (0.32) | CA1CA2CA4CA6BCHE | |
| SCHEMBL12952435 | 0.90 | CYP2B6 (0.33) | CA1CA2CA4CA6BCHE | |
| SCHEMBL13917695 | 0.89 | MMP12 (0.36) | CYP2B6CYP1A1CYP1A2CYP1B1DRD2 | |
| SCHEMBL12952438 | 0.89 | CYP2B6 (0.33) | CA1CA2CA4CA6BCHE | |
| SCHEMBL1011282 | 0.89 | CA1 (0.36) | CA1CA2CA4CA6BCHE | |
| SCHEMBL16421864 | 0.87 | BCHE (0.36) | BCHEACHECYP2B6MAP3K9MAP3K11 | |
| SCHEMBL13917696 | 0.84 | TDP2 (0.37) | ACHECYP2B6CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL10041131 | 0.84 | MEN1 (0.39) | CA1CA2CA4CA6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718754-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-2895896-B1 | A PHOTOCHROMIC ARTICLE HAVING AT LEAST PARTIALLY CROSSED POLARIZED PHOTOCHROMIC-DICHROIC AND FIXED-POLARIZED LAYERS | TRANSITIONS OPTICAL INC (US) | 2022-11-02 | — | — | EP | disclosed |