Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.34 |
| ▸ | MAP3K9 | P80192 | 5/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | MAP3K10 | Q02779 | 2/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29910296 | 0.89 | CA1 (0.36) | CA1CA2CA4CA6BCHE | |
| SCHEMBL1063519 | 0.89 | CA1 (0.36) | CA1CA2CA4CA6BCHE | |
| SCHEMBL29809978 | 0.89 | CA1 (0.36) | CA1CA2CA4CA6BCHE | |
| SCHEMBL13917703 | 0.83 | TDP2 (0.39) | CYP2B6 | |
| SCHEMBL13917701 | 0.81 | PNMT (0.32) | — | |
| SCHEMBL12952436 | 0.80 | CA1 (0.32) | CA1CA2CA4CA6BCHE | |
| SCHEMBL12952435 | 0.79 | CYP2B6 (0.33) | CA1CA2CA4CA6BCHE | |
| SCHEMBL13917695 | 0.79 | MMP12 (0.36) | CYP2B6 | |
| SCHEMBL16421864 | 0.79 | BCHE (0.36) | BCHEACHECYP2B6MAP3K9MAP3K11 | |
| SCHEMBL12952438 | 0.78 | CYP2B6 (0.33) | CA1CA2CA4CA6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686468-B2 | FOR USE IN SYNTHETIC RESINS TO OBTAIN VIOLET TO BLUE TINTS; USED IN PHOTOTROPIC GLASSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2004-02-03 | — | — | US | claimed |
| EP-1235823-B1 | H-ANNELLATED BENZO [F]CHROMENES | RODENSTOCK OPTIK G (DE) | 2003-07-16 | — | — | EP | claimed |
| US-9465234-B2 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-9465234-B2 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-9097916-B2 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-9097916-B2 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140225049-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140225049-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8741188-B2 | Ophthalmic devices comprising photochromic materials having extended pi-conjugated systems | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-8741188-B2 | Ophthalmic devices comprising photochromic materials having extended pi-conjugated systems | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130065056-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2013-03-14 | — | — | US | disclosed |
| US-20090072206-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-03-19 | — | — | US | disclosed |
| US-20090072206-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-03-19 | — | — | US | disclosed |
| US-20090032782-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2009-02-05 | — | — | US | disclosed |
| US-20090032782-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2009-02-05 | — | — | US | disclosed |
| US-20090032782-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2009-02-05 | — | — | US | disclosed |
| EP-1869140-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS | Johnson and Johnson Vision Care, Inc. (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006110513-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060226402-A1 | Ophthalmic devices comprising photochromic materials having extended PI-conjugated systems | KIM BEON-KYU | 2006-10-12 | — | — | US | disclosed |
| US-20060228557-A1 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | TRANSITIONS OPTICAL, INC. | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228557-A1 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | INCENP, PCNA, INTS6 | CA1 3180/4885CA2 3505/4885CA4 2525/4885 |
| US-20090032782-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | INTS6, INCENP, PCNA | CA1 3324/4885CA2 3524/4885CA4 2476/4885 |
| US-20130065056-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | INCENP, INTS6, IPO4 | CA1 3474/4885CA2 2575/4885CA4 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.