SCHEMBL29911017

SCHEMBL29911017

CCc1ccc(CC2OCCO2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
TP53 P04637 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
PLAU P00749 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP2A6 P11509 1/20 0.35
TRPA1 O75762 1/20 0.35
PLK1 P53350 1/20 0.35
IDO1 P14902 1/20 0.35
FKBP1A P62942 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363202 0.83 CYP1A2 (0.50) LMNASMN1; SMN2CYP2A6TRPA1FKBP1A
SCHEMBL21154704 0.83 ALDH1A1 (0.40) ALDH1A1LMNASMN1; SMN2RAB9ATAAR1
SCHEMBL13401236 0.82 TAAR1 (0.33) LPLLIPGALDH1A1LMNASMN1; SMN2
SCHEMBL13401242 0.80 TAAR1 (0.32) LPLLIPGALDH1A1LMNATP53
SCHEMBL21155257 0.80 ESR1 (0.44) ALDH1A1TAAR1CYP2C19IDO1
SCHEMBL14166113 0.80 TSHR (0.39)
SCHEMBL10311258 0.79 POLB (0.33) LPLLIPGTP53TAAR1CYP2A6
SCHEMBL8541016 0.78 HTR6 (0.43) ALDH1A1
SCHEMBL29910933 0.78 CA1 (0.38)
SCHEMBL7393096 0.78 HTR2A (0.37) SMN1; SMN2NPC1RAB9ATAAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115010693-A Preparation method of aryl acetaldehyde aldehyde 长沙资材科技有限公司 2022-09-06 CN disclosed