Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21155257 | 0.80 | ESR1 (0.44) | ALDH1A1CYP26A1 | |
| SCHEMBL14166113 | 0.80 | TSHR (0.39) | TSHR | |
| SCHEMBL27950337 | 0.78 | — | — | |
| SCHEMBL21154704 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7393096 | 0.78 | HTR2A (0.37) | MAPTMEN1KMT2A | |
| SCHEMBL29911017 | 0.78 | LPL (0.40) | ALDH1A1 | |
| SCHEMBL29910933 | 0.78 | CA1 (0.38) | — | |
| SCHEMBL22722 | 0.77 | GBA1 (0.42) | TSHR | |
| SCHEMBL3950312 | 0.76 | MAOB (0.46) | ALDH1A1CYP3A4TDP1MAPTMAOB | |
| SCHEMBL31207294 | 0.76 | ALDH1A1 (0.44) | HTR6ALDH1A1GFERCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512074-B1 | MOLECULES WITH ANTIBODY COMBINING SITES THAT CATALYSE HYDROLYSIS REACTIONS | SCRIPPS RESEARCH INST (US) | 1998-07-22 | — | — | EP | disclosed |
| EP-0512074-A4 | MOLECULES WITH ANTIBODY COMBINING SITES THAT CATALYSE HYDROLYSIS REACTIONS | — | 1993-07-14 | — | — | EP | disclosed |
| US-5187086-A | Molecules with antibody combining sites that catalyze hydrolysis reactions through use of a charged hapten | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0512074-A1 | MOLECULES WITH ANTIBODY COMBINING SITES THAT CATALYSE HYDROLYSIS REACTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-11-11 | — | — | EP | disclosed |
| WO-1991011512-A1 | MOLECULES WITH ANTIBODY COMBINING SITES THAT CATALYSE HYDROLYSIS REACTIONS | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1991-08-08 | — | — | WO | disclosed |