Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25408322 | 0.88 | MEN1 (0.41) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL26969083 | 0.82 | ALDH1A1 (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL26969090 | 0.81 | MEN1 (0.45) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL26969129 | 0.80 | MEN1 (0.44) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL3313601 | 0.77 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL30515585 | 0.77 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL7658562 | 0.76 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL16379679 | 0.75 | MEN1 (0.48) | L3MBTL1SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL16217176 | 0.75 | MEN1 (0.48) | L3MBTL1SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL24348526 | 0.74 | GRM5 (0.43) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416261-A1 | ETHANEDIAMINE-HETEROCYCLE DERIVATIVES AS INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES | UNIV TEXAS (US) | 2023-12-28 | — | — | US | disclosed |
| WO-2022192527-A1 | ETHANEDIAMINE-HETEROCYCLE DERIVATIVES AS INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416261-A1 | ETHANEDIAMINE-HETEROCYCLE DERIVATIVES AS INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES | PRMT1, PRMT7, PRMT5 | L3MBTL1 527/4885SMN1; SMN2 2849/4885CYP2C19 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.