Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986020 | 1.00 | TPMT (0.44) | TPMTHCAR1GPR139ACLYGPR35 | |
| SCHEMBL2039219 | 0.85 | PARP1 (0.38) | GPR35HCAR2PARP1POLB | |
| SCHEMBL985711 | 0.85 | PARP1 (0.38) | GPR35HCAR2PARP1POLB | |
| SCHEMBL3358922 | 0.83 | TPMT (0.55) | TPMTHCAR1HCAR2PARP1FLT1 | |
| SCHEMBL93282 | 0.83 | TPMT (0.62) | TPMTHCAR1HCAR2PARP1FLT1 | |
| SCHEMBL2171006 | 0.82 | TPMT (0.44) | TPMTHCAR1GPR139ACLYGPR35 | |
| SCHEMBL29912726 | 0.82 | TPMT (0.70) | TPMTHCAR1GPR139ACLYGPR35 | |
| SCHEMBL560354 | 0.82 | TPMT (0.70) | TPMTHCAR1GPR139ACLYGPR35 | |
| Hydrochloric Acid SCHEMBL28632192 | 0.80 | TPMT (0.59) | TPMTHCAR1HCAR2PARP1FLT1 | |
| SCHEMBL6246571 | 0.80 | TPMT (0.43) | TPMTHCAR1GPR139ACLYGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-115057843-B | Preparation method of chlorantraniliprole insecticide | 湖南化工研究院有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-115057843-A | Preparation method of chlorantraniliprole insecticide | 湖南化工研究院有限公司 | 2022-09-16 | — | — | CN | disclosed |